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Neomycin, Polymyxin B, and Gramicidin, Ophthalmic

What are other names for this medicine?

Type of medicine: antibiotic

Generic and brand names: neomycin, polymyxin B, and gramicidin, ophthalmic; AK-Spore Solution; Neosporin Ophthalmic Solution; Ocutricin Ophthalmic Solution

What is this medicine used for?

This medicine, in the form of eyedrops, is used to treat eye infections.

What should my health care provider know before I take this medicine?

Before taking this medicine, tell your health care provider if you have ever had an allergic reaction to any antibiotic, or if you allergic to mercury.

Tell your health care provider if you have herpes, chickenpox, or a virus infection of the eye.

Females of childbearing age: Tell your health care provider if you are pregnant, plan to become pregnant, or are breast-feeding.

How do I use it?

Use this medicine exactly as directed by your health care provider. Do not use more drops or use them more often than directed. Use the medicine until your health care provider tells you to stop.

Wash your hands thoroughly before applying medicine to your eyes. Tilt your head back, and gently pull your lower eyelid down to form a pouch. Hold the dropper above your eye, look up, and squeeze a drop of the medicine into the pouch. Close your eyes for a minute or two and with a fingertip press gently on the inside corner of your eye to keep the medicine from draining out. Do not rub your eyes.

To keep from contaminating the medicine, do not let the tip of the dropper touch your eye or any other surface. After use, put the cap on tightly. Do not use the medicine if it becomes discolored.

If you miss a dose, use it as soon as you remember unless it is almost time for the next scheduled dose. In that case, skip the missed dose and use the next one as directed. Do not use double doses. If you are not sure of what to do if you miss a dose, or if you miss more than one dose, contact your health care provider.

What should I watch out for?

Do not use this medicine for other eye conditions unless your health care provider approves. Do not share eye medicines with others.

If your eyes do not get better in a few days or if they get worse, contact your health care provider.

If you wear contact lenses, ask your health care provider if you can continue to wear them while you are using this medicine. Wait at least 15 minutes after using this medicine before putting in contacts.

What are the possible side effects?

Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your health care provider if you have any side effects that continue or get worse.

Serious (report these to your health care provider right away): Any new redness, irritation, or swelling that develops while you are using the medicine; rash; change in your vision; eye pain.

Other: Temporary burning or stinging feeling.

What products might interact with this medicine?

No significant drug interactions have been reported. However, be sure to tell your health care provider if you are using any other eye medicines. You may need to allow some time between applications of the different medicines.

Keep a list of all your medicines (prescription, nonprescription, supplements, natural remedies, and vitamins) with you. Be sure that you tell all health care providers who treat you about all the products you are taking.

How should I store this medicine?

Store this medicine at room temperature. Keep the container tightly closed. Protect it from heat, high humidity, and bright light.


This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your health care provider or pharmacist for more information or if you have any questions.

Ask your pharmacist for the best way to dispose of outdated medicine or medicine you have not used. Do not throw medicine in the trash.

Keep all medicines out of the reach of children.

Do not share medicines with other people.

Developed by McKesson Health Solutions LLC.
This content is reviewed periodically and is subject to change as new health information becomes available. The information is intended to inform and educate and is not a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional.
Copyright © 2003 McKesson Health Solutions LLC. All rights reserved.
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