Oprelvekin, Injection
What are other names for this medicine?
Type of medicine: interleukin (prevents low levels of platelets in the blood)
Generic and brand names: oprelvekin, injection; Interleukin 11, IL-11; Neumega
What is this medicine used for?
This medicine is given by injection (shots) to prevent thrombocytopenia (too few platelets in your blood). Platelets are blood cells that help form blood clots and stop bleeding. This medicine is given to people after chemotherapy treatment for certain types of cancer.
It may be used for other conditions as determined by your health care provider.
What should my health care provider know before I take this medicine?
Before taking this medicine, tell your health care provider if you have ever had:
- a brain tumor
- an allergy to any medicine
- an irregular heart rate
- heart disease
- liver or kidney disease
- lung disease
- problems with abusing alcohol.
Females of childbearing age: Tell your health care provider if you are pregnant or become pregnant while you are receiving these shots because it can harm the baby. Breast-feeding is not recommended during this treatment.
How do I use it?
The medicine comes as a powder and a liquid that you mix together. The shots are given once a day just below the surface of the skin.
Sometimes you can give yourself these shots or have someone at home give them to you. Be sure you know how and when to have shots and how much medicine to use. Use sterile, disposable syringes and needles. Use each syringe and needle only once and dispose of them safely, following your health care provider's instructions.
Carefully read and follow the directions that come in the package of medicine for preparing the shots. Wash your hands before using this medicine. Follow these steps to give yourself the shots:
- Your health care provider will tell you where you can give yourself the shots (abdomen, thigh, upper arm, or hip). If you are giving the shot in your abdomen, choose a site around the belly button but not in the belly button. Each day, choose a different spot for the shot to lessen irritation.
- Use an alcohol swab to clean the skin where you will give yourself the shot.
- Gently pinch up the skin and insert the needle into the skin at a 45° angle. After you insert the needle completely, release your grasp of the skin.
- Inject all of the solution by gently and steadily pushing down the plunger.
- After you have given yourself the shot, withdraw the needle and syringe and press an alcohol swab on the spot where the shot was given.
- Discard the syringe, needle, and drug vial. Use the syringes and needles ONLY ONCE. Throw them away after use. Put used needles in rigid puncture-resistant containers with lids or caps, such as heavy plastic bleach bottles with screw caps. DO NOT throw needles directly into garbage cans or dumpsters.
Read the information sheet that comes in the medicine package, and follow the instructions carefully. If you do not understand some of the instructions, ask your health care provider or pharmacist to explain.
What should I watch out for?
This medicine may cause swelling of your feet, ankles, or lower legs. If the swelling becomes severe, contact your health care provider.
Your health care provider will want to check your progress regularly. Keep all your appointments.
You may have shortness of breath when you exercise. This condition may improve after the first week of treatment, but it may continue until you stop this treatment.
What are the possible side effects?
Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your health care provider if you have any side effects that continue or get worse.
Serious (report these to your health care provider right away): Shortness of breath that gets worse, irregular heartbeat, severe swelling in your legs or feet, sudden weakness, numbness, slurred speech, confusion, blurred vision
Other: Nausea, vomiting, swelling, diarrhea, fever, headache, sore mouth, dizziness, fainting, cough, runny nose, rash, hives.
What products might interact with this medicine?
When you take this medicine with other medicines, it can change the way this or any of the other medicines work. Nonprescription medicines, vitamins, natural remedies, and certain foods may also interact. Using these products together might cause harmful side effects. Talk to your health care provider if you are taking:
- diuretics such as chlorothiazide (Diuril), hydrochlorothiazide (Esidrix, HydroDIURIL, Oretic), bendroflumethiazide (Naturetin), methyclothiazide (Enduron), indapamide (Lozol), metolazone (Zaroxolyn), chlorthalidone (Hygroton), furosemide (Lasix), bumetanide (Bumex), and torsemide (Demadex).
Keep a list of all your medicines (prescription, nonprescription, supplements, natural remedies, and vitamins) with you. Be sure that you tell all health care providers who treat you about all the products you are taking.
How should I store this medicine?
Store this medicine in the refrigerator but do not freeze. After you mix the medicine, store it in the refrigerator or at room temperature and use it within 3 hours. Keep the container tightly closed. Protect it from heat, high humidity, and bright light.
This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your health care provider or pharmacist for more information or if you have any questions.
Keep all medicines out of the reach of children.
Do not share medicines with other people.
