Page header image

Phentolamine, Injection

What are other names for this medicine?

Generic and brand names: phentolamine, injection; Regitine

What is this medicine used for?

This medicine is given by injection (shots) to prevent or control high blood pressure during surgery, which may occur if you have a condition called pheochromocytoma. This medicine may also be used as a test for pheochromocytoma.

This medicine is also used to prevent or control the destruction of tissue that can occur if certain medicines given by injection leak into nearby tissue. It may be used for other conditions as determined by your health care provider.

How do I use it?

You will be given this medicine by IV infusion (slow drip through a needle into your vein) or by injection (a shot). Your health care provider will give you the medicine.

If you are receiving this medicine as a test for pheochromocytoma, your health care provider will watch you closely for any reactions you may have.

What should I watch out for?

If you develop a fast or irregular heartbeat, contact your health care provider.

Females of childbearing age: Tell your health care provider if you are pregnant or plan to become pregnant. Do not breast-feed while taking this medicine without your health care provider's approval.

What are the possible side effects?

Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your health care provider if you have any side effects that continue or get worse.

Serious (report these to your health care provider): Fast or irregular heartbeat.

Other: Weakness, dizziness, flushing, nausea, vomiting, diarrhea, stuffy nose.

What products might interact with this medicine?

When you take this medicine with other medicines, it can change the way this or any of the other medicines work. Nonprescription medicines, vitamins, natural remedies, and certain foods may also interact. Using these products together might cause harmful side effects. Talk to your health care provider if you are taking:

  • epinephrine (Adrenalin)
  • ephedrine.

Keep a list of all your medicines (prescription, nonprescription, supplements, natural remedies, and vitamins) with you. Be sure that you tell all health care providers who treat you about all the products you are taking.


This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your health care provider or pharmacist for more information or if you have any questions.

Keep all medicines out of the reach of children.

Do not share medicines with other people.

Developed by McKesson Health Solutions LLC.
This content is reviewed periodically and is subject to change as new health information becomes available. The information is intended to inform and educate and is not a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional.
Copyright © 2003 McKesson Health Solutions LLC. All rights reserved.
Page footer image